prof. RNDr. Jan Vondráček, Ph.D.

2023

• Immortalized human MIHA hepatocyte cell line as a model for analysis of activation of nuclear receptors linked with disruption of lipid metabolism

  PETRÁŠ Jiří KABÁTKOVÁ Markéta RAPTOVÁ Petra LNĚNIČKOVÁ Anna VONDRÁČEK Jan

  Conference abstract

  Year: 2023, type: Conference abstract

• Switching on/off aryl hydrocarbon receptor and pregnane X receptor activities by chemically modified tryptamines

  SLÁDEKOVÁ Lucia ZGARBOVÁ Eliška VRZAL Radim VANDA David SOURAL Miroslav JAKUBCOVÁ Klára VÁZQUEZ-GÓMEZ Gerardo VONDRÁČEK Jan DVOŘÁK Zdeněk

  Article in Periodical

  Toxicology Letters, year: 2023, volume: vol. 387

2021

• A prolonged exposure of human lung carcinoma epithelial cells to benzo[a]pyrene induces p21-dependent epithelial-to-mesenchymal transition (EMT)-like phenotype

  HYZDALOVA Martina PROCHÁZKOVÁ Jiřina STRAPACOVA Simona SVRZKOVA Lucie VACEK Ondřej FEDR Radek ANDRYSÍK Zdeněk HRUBA Eva LIBALOVA Helena KLEMA Jiri TOPINKA Jan MASEK Josef SOUČEK Karel VONDRÁČEK Jan MACHALA Miroslav

  Article in Periodical

  Chemosphere, year: 2021, volume: 263, edition: January 2021, DOI

• Complex Alterations of Fatty Acid Metabolism and Phospholipidome Uncovered in Isolated Colon Cancer Epithelial Cells

  HOFMANOVÁ Jiřina SLAVIK Josef CIGANEK Miroslav OVESNÁ Petra TYLICHOVA Zuzana KARASOVÁ Martina ZAPLETAL Ondrej STRAKOVA Nicol PROCHAZKOVA Jirina BOUCHAL Jan KOLAR Zdenek EHRMANN Jiri LEVKOVA Monika HUSKOVA Zlatka SKALICKY Pavel KOZUBÍK Alois MACHALA Miroslav VONDRÁČEK Jan

  Article in Periodical

  International Journal of Molecular Sciences, year: 2021, volume: 22, edition: 13, DOI

• Changes in Sphingolipid Profile of Benzo[a]pyrene-Transformed Human Bronchial Epithelial Cells Are Reflected in the Altered Composition of Sphingolipids in Their Exosomes

  MACHALA Miroslav SLAVIK Josef KOVAC Ondrej PROCHÁZKOVÁ Jiřina PENCIKOVA Katerina PARENICOVA Martina STRAKOVA Nicol KOTOUCEK Jan KULICH Pavel MOLLERUP Steen VONDRÁČEK Jan HYZDALOVA Martina

  Article in Periodical

  International Journal of Molecular Sciences, year: 2021, volume: 22, edition: 17, DOI

2020

• Environmental six-ring polycyclic aromatic hydrocarbons are potent inducers of the AhR-dependent signaling in human cells

  VONDRÁČEK Jan PĚNČÍKOVÁ Kateřina CIGANEK Miroslav PIVNIČKA Jakub KARASOVÁ Martina HÝŽĎALOVÁ Martina STRAPÁČOVÁ Simona PÁLKOVÁ Lenka NEČA Jiří MATTHEWS Jason VOJTÍŠEK LOM Michal TOPINKA Jan MILCOVÁ Alena MACHALA Miroslav

  Article in Periodical

  Environmental Pollution, year: 2020, volume: 266, edition: November 2020, DOI

• Specific alterations of sphingolipid metabolism identified in EpCAM-positive cells isolated from human colon tumors

  PROCHÁZKOVÁ Jiřina SLAVIK Josef BOUCHAL Jan LEVKOVA Monika HUSKOVA Zlata EHRMANN Jiri OVESNÁ Petra KOLAR Zdenek SKALICKY Pavel STRAKOVA Nicol ZAPLETAL Ondrej KOZUBÍK Alois HOFMANOVÁ Jiřina VONDRÁČEK Jan MACHALA Miroslav

  Article in Periodical

  BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, year: 2020, volume: 1865, edition: 9, DOI

2019

• 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) Disrupts Control of Cell Proliferation and Apoptosis in a Human Model of Adult Liver Progenitors.

  SVOBODOVÁ Jana PROCHÁZKOVÁ Jiřina KABÁTKOVÁ Markéta KRKOŠKA Martin ŠMERDOVÁ Lenka LÍBALOVÁ Helena TOPINKA Jan KLÉMA Jiří KOZUBÍK Alois MACHALA Miroslav VONDRÁČEK Jan

  Article in Periodical

  TOXICOLOGICAL SCIENCES, year: 2019, volume: 172, edition: 2, DOI

• Butyrate interacts with benzo [a] pyrene to alter expression and activities of xenobiotic metabolizing enzymes involved in metabolism of carcinogens within colon epithelial cell models

  ZAPLETAL Ondřej PROCHÁZKOVÁ Jiřina DUBEC Vít HOFMANOVÁ Jiřina KOZUBÍK Alois VONDRÁČEK Jan

  Article in Periodical

  Toxicology, year: 2019, volume: 412, edition: JAN, DOI

• FUNCTIONAL ROLE OF AHR IN DIOXIN-MEDIATED DISRUPTION OF APOPTOSIS CONTROL IN A HUMAN MODEL OF ADULT LIVER PROGENITORS?

  KRKOŠKA Martin SVOBODOVÁ Jana KABÁTKOVÁ Markéta HYRŠLOVÁ Alena VONDRÁČEK Jan

  Conference abstract

  Year: 2019, type: Conference abstract