doc. RNDr. Luděk Eyer, Ph.D.

2022

• Guanine quadruplexes in the RNA genome of the tick-borne encephalitis virus: their role as a new antiviral target and in virus biology

  HOLOUBEK Jiří BEDNÁŘOVÁ Klára HAVIERNIK Jan HUVAROVÁ Ivana DVOŘÁKOVÁ Zuzana ČERNÝ Jiří OUTLÁ Martina SALÁT Jiří KONKOLOVA Eva BOURA Evzen RŮŽEK Daniel VORLÍČKOVÁ Michaela EYER Luděk RENČIUK Daniel

  Article in Periodical

  Nucleic Acids Research, year: 2022, volume: 50, edition: 8, DOI

• Monoclonal antibodies targeting two immunodominant epitopes on the Spike protein neutralize emerging SARS-CoV-2 variants of concern

  KOVACECH Branislav FIALOVA Lubica FILIPCIK Peter SKRABANA Rostislav ZILKOVA Monika PAULENKA-IVANOVOVA Natalia KOVAC Andrej PALOVA Denisa PAULIKOVA ROLKOVA Gabriela TOMKOVA Katarina TURIC CSOKOVA Natalia MARKOVA Karina SKRABANOVA Michaela SINSKA Kristina BASHEER Neha MAJEROVA Petra HANES Jozef PARRAK Vojtech PRCINA Michal CEHLAR Ondrej CENTE Martin PIESTANSKY Juraj FRESSER Michal NOVAK Michal SLAVIKOVA Monika BORSOVA Kristina CABANOVA Viktoria BREJOVA Bronislava VINAŘ Tomas NOSEK Jozef KLEMPA Boris EYER Luděk HÖNIG Václav PALUS Martin RŮŽEK Daniel VYHLIDALOVA Tereza STRAKOVÁ Petra MRAZKOVA Blanka ZUDOVA Dagmar KOUBKOVA Gizela NOVOSADOVA Vendula PROCHAZKA Jan SEDLACEK Radislav ZILKA Norbert KONTSEKOVA Eva

  Article in Periodical

  EBioMedicine, year: 2022, volume: 76, edition: February, DOI

• Porphyrins as potent inhibitors of the entry process of tick-borne encephalitis virus

  HOLOUBEK Jiří VANCOVÁ M RŮŽEK Daniel EYER Luděk

  Conference abstract

  Year: 2022, type: Conference abstract

2021

• Broad-Spectrum Antiviral Activity of 3'-Deoxy-3'Fluoroadenosine against Emerging Flaviviruses

  EYER Luděk SVOBODA Pavel BALVAN Jan VIČAR Tomáš RAUDENSKÁ Martina ŠTEFÁNIK Michal HAVIERNIK Jan HUVAROVÁ Ivana STRAKOVÁ Petra RUDOLF Ivo HUBÁLEK Zdeněk SELEY-RADTKE Katherine DE CLERCQ Erik RŮŽEK Daniel

  Article in Periodical

  Antimicrobial Agents and Chemotherapy, year: 2021, volume: 65, edition: 2, DOI

• Porphyrins and metalloporphyrins as potent inhibitors of the entry process of tick-borne encephalitis virus

  HOLOUBEK Jiří VANCOVÁ M RŮŽEK Daniel EYER Luděk

  Conference abstract

  Year: 2021, type: Conference abstract

2020

• FDA-Approved Drugs Efavirenz, Tipranavir, and Dasabuvir Inhibit Replication of Multiple Flaviviruses in Vero Cells

  ŠTEFÁNIK Michal VALDES James J. EZEBUO Fortunatus C. HAVIERNIK Jan UZOCHUKWU Ikemefuna C. FOJTÍKOVÁ Martina SALÁT Jiří EYER Luděk RŮŽEK Daniel

  Article in Periodical

  Microorganisms, year: 2020, volume: 8, edition: 4, DOI

• Tick-Borne Encephalitis Virus Vaccines Contain Non-Structural Protein 1 Antigen and may Elicit NS1-Specific Antibody Responses in Vaccinated Individuals

  SALÁT Jiří MIKULÁŠEK Kamil LARRALDE Osmany POKORNÁ FORMANOVÁ Petra CHRDLE Aleš HAVIERNIK Jan ELSTEROVÁ Jana TEISLEROVÁ Dana PALUS Martin EYER Luděk ZDRÁHAL Zbyněk PETRIK Juraj RŮŽEK Daniel

  Article in Periodical

  Vaccines, year: 2020, volume: 8, edition: 1, DOI

2019

• An E460D Substitution in the NS5 Protein of Tick-Borne Encephalitis Virus Confers Resistance to the Inhibitor Galidesivir (BCX4430) and Also Attenuates the Virus for Mice

  EYER Luděk NOUGAIREDE Antoine UHLÍŘOVÁ Marie DRIOUICH Jean-Sélim ZOUHAROVÁ Darina VALDÉS James J. HAVIERNIK Jan GOULD Ernest A. DE CLERCQ Erik DE LAMBALLERIE Xavier RŮŽEK Daniel

  Article in Periodical

  JOURNAL OF VIROLOGY, year: 2019, DOI

• Viral RNA-dependent RNA polymerase inhibitor 7-deaza-2'-C-methyladenosine prevents death in a mouse model of West Nile virus infection

  EYER Luděk FOJTÍKOVÁ Martina NENCKA Radim RUDOLF Ivo HUBÁLEK Zdeněk RŮŽEK Daniel

  Article in Periodical

  ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, year: 2019, volume: 63, edition: 3, DOI

2018

• Arbidol (Umifenovir): A Broad-Spectrum Antiviral Drug That Inhibits Medically Important Arthropod-Borne Flaviviruses

  HAVIERNIK Jan ŠTEFÁNIK Michal FOJTÍKOVÁ Martina KALI S TORDO N RUDOLF Ivo HUBÁLEK Zdeněk EYER Luděk RŮŽEK Daniel

  Article in Periodical

  Viruses, year: 2018, DOI