Mgr. Karel Souček, Ph.D.

2024

• Aryl hydrocarbon receptor as a drug target in advanced prostate cancer therapy - obstacles and perspectives

  PROCHÁZKOVÁ Jiřina KAHOUNOVA Zuzana VONDRÁČEK Jan SOUČEK Karel

  Article in Periodical

  TRANSCRIPTION-AUSTIN, year: 2024, DOI

• Discovery of Two Highly Selective Structurally Orthogonal Chemical Probes for Activin Receptor-like Kinases 1 and 2

  NĚMEC Václav REMEŠ Marek BEŇOVSKÝ Petr BÖCK Michael Christopher ŠRANKOVÁ Eliška WONG Jong Fu JULIEN Cros WILLIAMS Eleanor TSE Lap Hang SMIL David ENSAN Deeba ISAAC Methvin B AL-AWAR Rima GOMOLKOVÁ Regína URSACHI Vlad-Constantin FAFÍLEK Bohumil KAHOUNOVA Zuzana VICHOVA Rachel VACEK Ondrej BERGER Benedict-Tilman WELLS Carrow I CORONA Cesear R VASTA James D ROBERS Matthew B KREJČÍ Pavel SOUČEK Karel BULLOCK Alex N KNAPP Stefan PARUCH Kamil

  Article in Periodical

  Journal of Medicinal Chemistry, year: 2024, volume: 67, edition: 15, DOI

• Lipidomic analysis of tetraspanin-deficient extracellular vesicles

  SMOLKO Martin KOVÁČ Ondrej VYHLÍDALOVÁ KOTRBOVÁ Anna BÖHMEOVÁ Nina CELÁ Anežka KOTOUČEK Jan SOUČEK Karel BRYJA Vítězslav HLAVÁČKOVÁ POSPÍCHALOVÁ Vendula

  Conference abstract

  Year: 2024, type: Conference abstract

• Lipidomic profiling of extracellular vesicles from tetraspanin-deficient cell lines

  SMOLKO Martin KOVÁČ Ondrej VYHLÍDALOVÁ KOTRBOVÁ Anna BÖHMEOVÁ Nina CELÁ Anežka KOTOUČEK Jan SOUČEK Karel BRYJA Vítězslav HLAVÁČKOVÁ POSPÍCHALOVÁ Vendula

  Conference abstract

  Year: 2024, type: Conference abstract

• Orthotopic model for the analysis of melanoma circulating tumor cells

  PÍCKOVÁ Markéta KAHOUNOVÁ Zuzana RADASZKIEWICZ Tomasz Witold PROCHÁZKOVÁ Jiřina FEDR Radek NOSKOVÁ Michaela RADASZKIEWICZ Katarzyna Anna OVESNÁ Petra BRYJA Vítězslav SOUČEK Karel

  Article in Periodical

  Scientific Reports, year: 2024, volume: 14, edition: 1, DOI

• Proteomic analysis of tetraspanin-deficient extracellular vesicles

  RAKYTOVÁ Janka SMOLKO Martin VYHLÍDALOVÁ KOTRBOVÁ Anna GÖMÖRYOVÁ Kristína CELÁ Anežka KOTOUČEK Jan PUSTKA Václav ZDRÁHAL Zbyněk SOUČEK Karel BRYJA Vítězslav HLAVÁČKOVÁ POSPÍCHALOVÁ Vendula

  Conference abstract

  Year: 2024, type: Conference abstract

• Single-cell profiling of surface glycosphingolipids opens a new dimension for deconvolution of breast cancer intratumoral heterogeneity and phenotypic plasticity

  PROCHAZKOVA Jirina FEDR Radek HRADILOVÁ Barbora KVOKAČKOVÁ Barbora SLAVIK Josef KOVAC Ondrej MACHALA Miroslav FABIAN Pavel NAVRATIL Jiri KRACALIKOVA Simona LEVKOVA Monika OVESNÁ Petra BOUCHAL Jan SOUČEK Karel

  Article in Periodical

  JOURNAL OF LIPID RESEARCH, year: 2024, volume: 65, edition: 9, DOI

2023

• Circulating tumor cell-derived preclinical models: current status and future perspectives

  KAHOUNOVÁ Zuzana PÍCKOVÁ Markéta DRÁPELA Stanislav BOUCHAL Jan SZCZYRBOVÁ Eva NAVRÁTIL Jiří SOUČEK Karel

  Article in Periodical

  Cell Death and Disease, year: 2023, volume: 14, edition: 8, DOI

• CRISPR CAS9 ENGINEERED TETRASPANIN DEFICIENT CELL LINES FOR THE ANALYSIS OF EXTRACELLULAR VESICLES

  SMOLKO Martin VYHLÍDALOVÁ KOTRBOVÁ Anna CELÁ Anežka KOTOUČEK Jan SOUČEK Karel BRYJA Vítězslav HLAVÁČKOVÁ POSPÍCHALOVÁ Vendula

  Conference abstract

  Year: 2023, type: Conference abstract

• Prognostic value and multifaceted roles of tetraspanin CD9 in cancer

  ONDRUŠŠEK Róbert KVOKAČKOVÁ Barbora KRYŠTOFOVÁ Karolína BRYCHTOVÁ Světlana SOUČEK Karel BOUCHAL Jan

  Article in Periodical

  Frontiers in Oncology, year: 2023, volume: 13, edition: March 2023, DOI