Project information
Genetic risk prediction to sepsis in children
- Project Identification
- GP301/03/D196
- Project Period
- 9/2003 - 8/2006
- Investor / Pogramme / Project type
-
Czech Science Foundation
- Postdoctoral projects
- MU Faculty or unit
- Faculty of Medicine
- Keywords
- sepsis, gene, polymorphism, children
The polymorphism of genes encoding protein receptors on immune system cells plays an important role in surviving sepsis. Some of the most iportant are lipopolysacharide binding protein, bactericidal permeability increasing protein, toll-like receptors and tumor necrosis factor beta. It has been demostrated recently that some variants of these genes are frequently associated with severe infections, development of sepsis, multiorgan failure and death.
Publications
Total number of publications: 4
2007
-
Modeling effect of the septic condition and trauma on C-reactive protein levels in children with sepsis: a retrospective study
Critical Care, year: 2007, volume: 11(3), edition: 2007
-
Vliv závažnosti septického stavu a traumatu na dynamiku C-reaktivního proteinu a leukocytů u septických stavů u dětí
Třetí česko-slovenský kongres dětské intenzivní medicíny a anestezie, year: 2007
2006
-
Prediction of risk of sepsis based on deviance in MGLM
IWSM 2006, Proceedings of the 21st International Workshop on Statistical Modelling, year: 2006
2005
-
Užití mnohorozměrného zobecněného lineárního modelu ke klasifikaci objektů
XXIII. mezinárodní kolokvium o řízení osvojovacího procesu, year: 2005