Project information
The role of homologues, p73, p63 and KET proteins, in cell cycle, malignant transformation of the cell and apoptosis
- Project Identification
- NC6404
- Project Period
- 1/2000 - 1/2002
- Investor / Pogramme / Project type
-
Ministry of Health of the CR
- R&D of Oncology
- MU Faculty or unit
-
Faculty of Medicine
- Cooperating Organization
-
University Hospital Brno-Bohunice
- Responsible person MUDr. Rudolf Nenutil, CSc.
- Responsible person RNDr. Bořivoj Vojtěšek, DrSc.
One of our major interests is to study the functions of p73alpha,p73beta,KET and p63 homologues of p53 tumour suppressor in developmental and cell cycle regulation, in tumour biology as well as functional interactions among these proteins. We will study the interactions between the p53 homologues and scDNA.