Informace o projektu
Involvement of Czech Translational Medicine Infrastructure to the European Advanced Translational Research Infrastructure in Medicine
(EATRIS-ERIC-CZ)
- Kód projektu
- LM2018133
- Období řešení
- 1/2020 - 12/2022
- Investor / Programový rámec / typ projektu
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Ministerstvo školství, mládeže a tělovýchovy ČR
- Velké infrastruktury pro výzkum, vývoj a inovace
- Fakulta / Pracoviště MU
- Středoevropský technologický institut
- Spolupracující organizace
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Mikrobiologický ústav AV ČR, v. v. i.
Ústav experimentální medicíny AV ČR, v. v. i.
Ústav jaderné fyziky AV ČR, v. v. i.
Ústav makromolekulární chemie AV ČR, v. v. i.
Ústav organické chemie a biochemie AV ČR, v. v. i.
Univerzita Karlova
Univerzita Palackého v Olomouci
- Odpovědná osoba doc. MUDr. Marián Hajdúch, Ph.D.
In 2011, the Czech Republic acceded to the European Advanced Translational Research Infrastructure in Medicine (EATRIS) consortium and this transitional phase lasted even in 2013. EATRIS entered in fall 2013 to ERIC (EATRIS-ERIC) and the Czech Republic became one of the founding countries. At the national level, the national node was built according to the schedule in 2010-2014 (Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University Olomouc - IMTM), and in 2013/2014 we have created the national network, where the following institutions joined: Institute of Chemical Technology Prague (ICT), Institute of Organic Chemistry and Biochemistry AS CR, v.v.i. (IOCB), Charles University in Prague, First Faculty of Medicine (CU), Institute of Macromolecular Chemistry AS CR, v.v.i. (IMC), Masaryk University, Central-European Technology Institute (CEITEC), Nuclear Physics Institute of the ASCR, v.v.i. (NPI), Institute of Microbiology AS CR, v.v.i. (IM). Majority of these institutions have already signed an access agreement to EATRIS-ERIC (http://www.eatris.eu/about/simpleinstitutions.html). Czech institutions are actively involved in the activities of platforms Small Molecules, Biomarkers, Vaccines, and Imaging and Tracing. The mission of the current infrastructure project proposal EATRIS-ERIC-CZ is to further develop a dynamic and collaborative environment that will support chemical, biomedical, and clinical research, and speed up its transfer into clinical practice. It will connect and facilitate collaboration of top national research institutions and hospitals in the research partnership. EATRIS-ERIC-CZ will lead to the development of new knowledge and it will place the Czech Republic among nationally and internationally recognized centres of excellence in molecular and translational medicine directly linked to EATRIS-ERIC and other major biomedical infrastructures.
Cíle udržitelného rozvoje
Masarykova univerzita se hlásí k cílům udržitelného rozvoje OSN, jejichž záměrem je do roku 2030 zlepšit podmínky a kvalitu života na naší planetě.
Publikace
Počet publikací: 21
2022
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New-Generation Heterocyclic Bis-Pentamethinium Salts as Potential Cytostatic Drugs with Dual IL-6R and Mitochondria-Targeting Activity
Pharmaceutics, rok: 2022, ročník: 14, vydání: 8, DOI
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Nociceptin/orphanin FQ opioid receptor (NOP) selective ligand MCOPPB links anxiolytic and senolytic effects
GEROSCIENCE, rok: 2022, ročník: 44, vydání: 1, DOI
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Non-psychotropic cannabinoids as inhibitors of TET1 protein
Bioorganic Chemistry, rok: 2022, ročník: 124, vydání: July 2022, DOI
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Pentamethinium salts suppress key metastatic processes by regulating mitochondrial function and inhibiting dihydroorotate dehydrogenase respiration
Biomedicine & Pharmacotherapy, rok: 2022, ročník: 154, vydání: October 2022, DOI
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Very rare near-haploid acute lymphoblastic leukemia resistant to immunotherapy and CAR-T therapy in 19-year-old male patient
CLINICAL CASE REPORTS, rok: 2022, ročník: 10, vydání: 3, DOI
2021
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Cross-oncopanel study reveals high sensitivity and accuracy with overall analytical performance depending on genomic regions
GENOME BIOLOGY, rok: 2021, ročník: 22, vydání: 1, DOI
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Distribution of SARS-CoV-2 Lineages in the Czech Republic, Analysis of Data from the First Year of the Pandemic
Microorganisms, rok: 2021, ročník: 9, vydání: 8, DOI
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Hypermethylation of CD19 promoter enables antigen-negative escape to CART-19 in vivo and in vitro
Journal for ImmunoTherapy of Cancer, rok: 2021, ročník: 9, vydání: 8, DOI
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Novel Mitochondria-targeted Drugs for Cancer Therapy
Mini-reviews in medicinal chemistry, rok: 2021, ročník: 21, vydání: 7, DOI
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T-Cell Activation: Post-Infection Diagnostic Tool for COVID-19
Folia biologica, rok: 2021, ročník: 67, vydání: 1